Home > News > Content

Cosmetic Packaging Sterilization Process Analysis

Jun 24, 2018

For  the cosmetics industry in China cosmetic bottle sterilization and  disinfection for many years, delay the use of old technology and there  is a flaw in the situation, learn from the international advanced  disinfection industry, follow the Ministry of Health to develop "GMP  validation guidelines" and "disinfection technical specifications"  requirements, design and manufacture "JZCF-B" series packaging container ozone disinfection system has obvious disinfection effect. Cosmetic packaging containers require advanced sterilization process analysis;

 First, the principle of ozone sterilization

    Ozone sterilization is a biochemical oxidation reaction. Ozone  oxidation decomposes the enzymes necessary for oxidizing glucose inside  the bacteria; it can also directly interact with bacteria and viruses,  destroying cell walls and ribonucleic acids, and breaking down  macromolecule polymers such as DNA, RNA, proteins, lipids, and  polysaccharides. The  process of material metabolism growth and reproduction is destroyed; it  can also penetrate cell membrane tissue, invade the cell membrane and  act on the outer membrane lipoprotein and internal lipopolysaccharide,  causing the cell to undergo permeability distortion, leading to cell  lysis and death, and will die. The  genetic, parasitic, parasitic virion, bacteriophage, mycoplasma, and  pyrogens (bacterial viral metabolites, endotoxins), etc. Throughout  the perspective of aseptic technology on the role of microorganisms can  be divided into three kinds of antibacterial, bactericidal and  bacteriolytic, application of ozone as a sterilizing agent is  bacteriolytic.

   In  the “Disinfection Technical Specifications” promulgated by the Ministry  of Health in 1991, there is also a description of the principle of  ozone sterilization:

"Scientific  research shows that ozone has a very strong bactericidal effect."  "Ozone is unstable under normal temperature and atmospheric pressure and  quickly decomposes itself into oxygen (O2) and a single oxygen atom  (O). The latter is very strong. Active,  it has a strong oxidizing effect on bacteria.Oxygen oxidation breaks  down the enzymes necessary for oxidizing glucose inside the bacteria,  destroys the cell membrane, kills it, and the excess oxygen atoms will  recombine themselves into ordinary oxygen molecules (O2). There  is no toxic residue, so it is called 'pollution-free disinfectant'. It  not only has a strong ability to kill a variety of bacteria (including  hepatitis virus, E. coli, green bacilli, and bacteria, etc.), but also  kills. Mold is also very effective."